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UFC 321 Predictions: Tom Aspinall vs Ciryl Gane and Full Fight Card Analysis

October 25, 2025

The United Fighting Championship 321, taking place at the Etihad Arena in Abu Dhabi, will feature the heavyweight title fight with Tom Aspinall defending his title against all-time challenger Ciryl Gane. This, in addition to a women’s strawweight fight for a title, and other fights with title implications, should be very exciting for MMA fans.

Main Event: Aspinall vs Gane

Tom Aspinall, the undisputed heavyweight champion, will be defending his title for the first time after being named the champion when Jon Jones vacated when he retired. Aspinall has been nothing short of dominant in the UFC since he joined, as 14 of his victories have been in the first round. Aspinall’s fighting style and success can be influenced by his punching power and well-rounded grappling capabilities, which means he can be a threat, if not a nightmare, for anyone he fights.

Expert Predictions for Main Event

While the majority predict Aspinall to defend his title likely by a late stoppage as he has been finishing fights quickly lately, should he and Gane engage in high-level striking, we may see a prolonged affair with Gane’s technique and game plan allowing him to survive longer than most but his ground game gives Aspinall a clear advantage. For the most part, this fight could be viewed as a hard-pressing fight from Aspinall versus the technical and calculated approach from Gane.

Co-Main Event: Women’s Strawweight Title

The vacant women’s strawweight title bout is between Virna Jandiroba and Mackenzie Dern and the winner takes the title. Jandiroba also comes in on a five-fight win-streak, likely confident, though she previously lost to Dern before. Even though stylistically both are Brazilian jiu-jitsu black belts, Dern will be favored going into this fight, not just because of her win to Jandiroba, but Dern also has shown to improve her striking over the last several fights.

Betting Odds and Final Thoughts

Given Aspinall’s record and ability to finish fight, it’s no surprise Aspinall is the heavy favorite at -345 versus Gane’s +275. Expert betting advice here might suggest Aspinall with some picks from the undercard bouts to balance the bets instead of betting straight on Aspinall if you do decide to place a bet.